The overwhelming majority is purulent - inflammatory diseases cause cocci, i.e. microorganisms having the spherical (spherical) form. Them divide on two greater groups - grampositive and gramnegative. Inside of these groups allocate aerobic and facultatively - anaerobic cocci and anaerobic cocci.

Among grampositive aerobic and facultatively - anaerobic cocci the greatest value microorganisms of family Micrococcaceae (sort Staphylococcus) and have families Streptococcaceae (sort Streptococcus), among gramnegative aerobic and facultatively - anaerobic cocci - representatives of family Neisseriaceae (N.gonorrhoeae - honococc and N.meningitidis - meningococcus). Among grampositive anaerobic coccus the greatest value have peptococcus и пептострептококки, among gramnegative anaerobic coccus - veillonell.

Metaphysical representation about the nature of development - R.Virkhov. The dialectic concept - for the first time Gegel - the law of unity and conflict of opposites. Гиппократ has allocated 2 beginnings in illness: patos et ponos. Мечников - the main reason of an inflammation of an infection - struggle of two essences (¼¬/about; m/about). A macroorganism: stimulation лейкопоэза, change of circulation, increases number лейкоцитозов in a peripheral zone of a vessel - regional standing of leukocytes. A microorganism: toxins, мембранные components.
Pauls the law of unity and conflict of opposites as for the first time has formulated motive powers(forces) of development of illness. Its(his) concept: on the one hand the phenomena of damage, with another - явл. Protection and indemnifications. An example: an anemia - a tachycardia, a spasm of peripheral vessels, increase of breath, etc. in a counterbalance to loss of blood.

Historically changed perceptions of disease.Disease - deviation from the norm of the average type (one of the first definitions).
Ado: Norma - form of life that provides the best action.
Rudolf Virchow: Illness - lives in abnormal conditions of existence.
The main criterion for the disease - the existence of gross morphological changes (violations).
The main criterion for the disease - a violation disability. Communications, balancing with the external environment is reduced by disease.
Pavlov, Mechnikov, Speransky: When the disease along with compensation for damage to evolve reaction.
Marks: The disease - tight in their lives freedom.